These next few verses wind up being breeding ground for lots of contention. Some have inappropriately used these verses to show that Jacob was “saved” and Esau “damned to hell”. It seems to me that this ignores Paul’s argument at this stage of his defense of the righteousness of God: that being, God’s Word stands and now, why it stands.
Paul has us look at Rebekah and Isaac’s situation (Gen 25:21-26). Here she is finally pregnant, and God be praised, with fraternal twins! The question about God’s Promise comes up: do they split Abraham’s inheritance? What if one of them is wicked or one of them careless…how will God’s Word stand if these men are faulty?